Built with QPPVs · GVP Module VI · ICH E2B(R3) · SAHPRA Compatible

Process your ICSRs
5× faster.
AI-powered pharmacovigilance
for pharma SMEs.

The AI pharmacovigilance platform for pharma SMEs and biotechs who cannot afford a missed deadline or a coding error to jeopardise their MA. NLP extraction · MedDRA AI coding · CIOMS I & E2B(R3) · 6 authorities.

No commitment 15-min setup Data hosted in Europe
PharmaVeil — ICSR Processing
AI active
Manual reading and transcription of the email
~25 min
📖
Manual MedDRA term lookup in the dictionary
~15 min
📝
Manual completion of CIOMS I form
~20 min
🔍
Manual duplicate check in the database
~10 min
Total: ~70 min / case · Human error risk
1
AI intake & extraction
Patient, drug, effect — automated
12 sec
2
MedDRA coding + seriousness
PT term suggested, confidence score displayed
8 sec
3
Human validation
Pre-filled form, editable if needed
~65 sec
4
CIOMS I PDF export + audit trail
Ready to submit, automatically archived
3 sec
Total: ~90 seconds / case · 97% faster
Saving: ~68 min per case · 97% time saved
Compliance
GVP Module VI
EudraVigilance
MedDRA 27.0
ICH E2B(R3)
RGPD
21 CFR Part 11
GAMP 5
HDS (health data)
97%
Reduction in processing time per case
0
Regulatory deadline missed in production
98%
NLP accuracy on the 4 GVP mandatory fields
15 min
To get started, no extra infrastructure needed
How it works

Three steps.
One case processed.

No changes to your existing infrastructure. No safety database required to get started. Operational in 15 minutes.

01
📥

Automated intake

Forward your notification emails to your dedicated PharmaVeil address, upload a scanned CIOMS I form, or use our integrated web form.

Email · PDF · Web form
02
🤖

AI extraction & coding

Our NLP agent identifies the 4 mandatory GVP elements (patient, reporter, drug, effect), suggests the MedDRA term with a confidence score and calculates the regulatory deadline.

NLP + LLM + MedDRA 27.0
03

Human validation & rapport

You review the pre-filled form field by field (colour-coded confidence), edit if necessary and validate. The CIOMS I PDF report is generated with a full audit trail.

CIOMS I · E2B(R3) · Audit trail
Features

Built for real-world PV.
Not a generic tool adapted.

Every feature was co-built with active QPPVs and Drug Safety Officers. No unnecessary features. Only what a PV team needs every day.

🧠

Multilingual NLP agent

Reads and extracts data from emails, scanned PDFs and forms. Optimised for French and English. German and Spanish planned Q4 2026.

FR · EN DE · ES Q4 2026
🏷️

Assisted MedDRA coding

PT/LLT term suggestions with confidence score. MedDRA 27.0 dictionary integrated. Colour code: green (high confidence), orange (to review). 1-click validation.

MedDRA 27.0 · Score confiance

Automatic GVP deadline alerts

Automatic 7/15/90-day deadline calculation based on case seriousness at intake. Real-time deadline and backlog dashboard. Automatic D-3 and D-1 email alerts sent to the QPPV. Zero serious cases missed.

GVP Module VI · 7/15/90d · Email D-3/D-1
📄

Multi-authority CIOMS I & E2B(R3) export

Signed CIOMS I PDF report ready to submit. E2B(R3) XML natively adapted for 6 authorities: EudraVigilance (EMA), MHRA-YC (UK), Health Canada Vigilance, ANSM, FDA/FAERS and SAHPRA. Electronic signature 21 CFR Part 11 compliant.

CIOMS I · E2B(R3) · 6 authorities
🔍

AI duplicate detection

Smart deduplication algorithm on patient + drug + effect + time window (Claude AI). Visual banner before validation if a potential duplicate is detected, with direct link to the similar case. On-demand re-check available.

Claude AI · Visual banner
📊

PSMF dashboard & audit trail

Real-time view of backlog, current deadlines and compliance rate. Full audit trail compliant with 21 CFR Part 11. Exportable for your PSMF and inspections.

PSMF · 21 CFR Part 11
Integrated PV expertise

Not just intake.
The full craft.

PharmaVeil doesn't stop at data collection. The platform integrates the scientific tools a QPPV uses every day — causality assessment, interaction management, patient history, automatic follow-up letters and signal detection.

🎯

Naranjo + WHO-UMC causality assessment

Naranjo algorithm (10 questions, score auto-calculated) and WHO-UMC scale in parallel. Automatic classification: definite, probable, possible, doubtful. Q9 pre-filled from the patient's medical history.

Naranjo · WHO-UMC
💊

Concomitant medications & interactions

Automatic NLP extraction of co-medications from the narrative. Built-in drug interaction database. Visual alerts before validation when a critical interaction is detected. E2B(R3) export automatically updated.

NLP · Interaction database
📋

Patient medical history (B.2)

Manual entry or NLP extraction of medical history, allergies and concurrent conditions. Auto-feeds Naranjo Q9. Compliant with ICH E2B(R3) section B.2 — ready for export.

Section B.2 · NLP extraction
📨

Automatic follow-up letters

Automatic detection of missing E2B fields. PDF generation for 4 letter types (initial, D+7, D+14, escalation) with daily cron. No more forgotten incomplete cases — the system chases reporters for you.

Auto PDF · Cron D+0/D+7/D+14
📡

Signal detection & line listings

Pharmacovigilance signal management module and aggregated line listings by INN, MedDRA PT or time period. "Self-reporter" toggle for self-reported cases. Supports EMA proactive signal detection requirements.

Signal management · Listings
📰

RegIntel — live regulatory watch

Real-time RSS feeds from 4 authorities (MHRA, FDA, ANSM, SAHPRA) digested daily by AI. Filtering by client profile (INN, country, vigilance type). No need to manually monitor 30 regulatory websites.

MHRA · FDA · ANSM · SAHPRA
ROI Calculator

How much does PharmaVeil save you?

Based on an average hourly cost of €65/h for a Drug Safety Officer profile and 70 min of manual processing per case per TransCelerate benchmarks.

ICSR cases per month 50
DSO hourly cost (€) 65 €
Current manual time (min/case) 70 min
Current monthly cost
manual processing only
3 792 €
Monthly cost with PharmaVeil
processing + Pro subscription
613 €
Monthly saving
3 179 €
12-month ROI
+518%

* Indicative calculation: 90 sec/case with PharmaVeil vs indicated manual time. Includes Pro subscription at €1,499/month. Excludes savings on regulatory penalties and reduced error risk.

Security & Compliance

Built for the most demanding
regulated environments.

Pharmacovigilance handles sensitive health data. PharmaVeil was architected from the ground up to meet the requirements of auditors, inspectors and QPPVs globally.

🏥

Health Data Hosting (HDS)

Your pharmacovigilance data is health data under GDPR. It is hosted exclusively on HDS-certified servers in France within the European Union.

  • ISO 27001 & HDS certified datacentres in France
  • Data never transferred outside the EU
  • AES-256 encryption at rest and in transit (TLS 1.3)
  • Daily backups, 7-year retention
  • DPA (Data Processing Agreement) provided on request
📋

Pharma regulatory compliance

PharmaVeil is designed to integrate into your validated quality system. We provide the documentation your QA team needs for system qualification.

  • GVP Module VI compliant (ICH E2B R3)
  • Full audit trail compliant with 21 CFR Part 11
  • GAMP 5 validation documentation (IQ/OQ/PQ)
  • System qualification report (IQ/OQ) provided
  • Audit log access for your inspections
🔒

Data isolation & confidentiality

Each PharmaVeil client has a fully isolated environment. Your data is never shared or used to train global AI models.

  • Dedicated tenant per client (full isolation)
  • No data used for AI training
  • RBAC access control (roles and permissions)
  • Mandatory 2FA authentication Q4 2026
  • Configurable automatic session expiry
🤝

Human-in-the-loop model

PharmaVeil's AI never submits a case autonomously. Every MedDRA coding decision and every submission requires explicit human validation — in line with CIOMS WG XIV recommendations (2024).

  • Human validation obligatoire avant toute soumission
  • Confidence score displayed for every AI suggestion
  • Traceability: who validated what, when
  • Compatible with GVP Article 28 requirements
  • CIOMS Working Group XIV consensus 2024 compliant
Trusted by

Validated by QPPVs
and Drug Safety Officers.

★★★★★

"PharmaVeil solves exactly the daily problem of small PV teams: too many cases, not enough resources, relentless regulatory deadlines. The demo on our own cases convinced us in 20 minutes."

👩‍⚕️
Dr. S. Moreau
QPPV · ex-regulatory authority · 18 years PV experience
★★★★★

"The MedDRA suggestion with confidence score is exactly what I was looking for. It doesn't replace the coder's expertise — it enhances it and reduces lookup time by 80%."

👨‍💼
M. Blanc
Drug Safety Officer · Mid-cap pharma
★★★★★

"The PSMF-ready dashboard transformed our audit preparations. What used to take a full day of compilation now takes 10 minutes. The audit trail is exactly what inspectors expect."

👩‍🔬
Dr. K. Dubois
Head of Regulatory Affairs · EU Biotech
Pricing

Simple. Predictable.
No per-case fees.

Unlike most players, PharmaVeil charges a flat monthly subscription. Your cost never fluctuates with your case volume.

Starter
€499/month
Startups · Small teams · Lean portfolios · 2 users
  • Core PV
  • ICSR management (email, PDF, XML, manual)
  • NLP extraction + MedDRA coding
  • CIOMS I PDF + E2B(R3) XML export
  • Pre-Submission Check (authority rules)
  • GVP deadline alerts (7/15/90 days)
  • PV expertise
  • Naranjo + WHO-UMC causality
  • Concomitant medications + interactions
  • Patient medical history (B.2)
  • Automatic follow-up letters (D+0/D+7/D+14)
  • Signal detection
  • MLM literature screening (2 sources/month) Q4 2026
  • RegIntel
  • Regulatory database access (read-only)
  • Client profile filtering
  • Support
  • Email · 48h · Self-service
Most popular
Pro
€1,499/month
→ Pricing on request based on volume
Established pharma SMEs · Medium to high volume · 5 users
  • Everything in Starter, plus:
  • E2B(R3) multi-authority connectivity (EMA, MHRA, ANSM, Health Canada, FDA, SAHPRA)
  • Direct Gateway AS2 submission + ACK tracking 2027
  • Signal detection
  • Automated multi-source MLM (unlimited) Q4 2026
  • PV detection via OCR + NLP (incoming flows)
  • Signal detection & aggregated line listings
  • RegIntel
  • Full regulatory watch (4 vigilance types)
  • Client profile filtering (INN, country, vigilance)
  • Traceability & Audit Trail — inspection-ready
  • Support
  • Email + Chat · 24h · Guided onboarding
Enterprise
Custom
Let's talk
International labs · Clinical trials · Pricing tailored to your scope
  • Everything in Pro, plus:
  • Clinical trial compliance (SAE/SUSAR — full workflow) Q4 2026
  • PMDA (Japan) E2B adapter 2027
  • Support & SLA
  • Dedicated Customer Success Manager
  • 4h SLA · GxP validation documentation
  • Team training included
🛡
The Inspection-Ready argument

"With PharmaVeil Pro, you address the 3 mandatory signal detection sources required by the EMA: spontaneous reports (Core PV) ✓, unstructured incoming flows (OCR+NLP) ✓, and scientific literature (MLM Screening — manual import today, multi-source automation Q4 2026). At your next inspection, your process is traced, logged and auditable in a single platform."

FAQ

Frequently asked questions.

Does PharmaVeil replace my safety database (ARISg, Argus Safety)? +
No. PharmaVeil is an automation agent that sits upstream of your safety database. It automates intake, NLP extraction and pre-filling. The E2B(R3) XML export allows the case to be imported into your existing safety database without re-entry. On the Starter plan, you can also operate without a safety database for small volumes.
Is AI validation compatible with GVP requirements? +
Yes, under the "Human-in-the-loop" model. The AI pre-fills, the human validates every field before any submission. This is exactly the framework recommended by the CIOMS Working Group XIV (2024 Consensus Report) and fully compatible with GVP Module VI. The full audit trail documents every human action, satisfying EMA, MHRA and SAHPRA inspection requirements.
Where is my pharmacovigilance data hosted? +
Exclusively on HDS (Health Data Hosting) and ISO 27001 certified servers in France. Your data never leaves European Union territory. Full GDPR compliance. A DPA (Data Processing Agreement) is provided upon contract signature.
How accurate is the automated MedDRA coding? +
Our model achieves 94–98% accuracy on common PT terms, validated on over 2,000 real cases. For complex cases or rare terms, the confidence score is clearly displayed in orange — the coder instantly knows when to review. The AI never submits alone: human validation is always mandatory, regardless of model confidence.
Does PharmaVeil include Naranjo and WHO-UMC causality assessment? +
Yes, both. The Naranjo algorithm (10 questions, auto-calculated score) and WHO-UMC scale are integrated directly into the case file — no parallel Excel spreadsheet needed. Naranjo Q9 (role of concomitant medications) is pre-filled automatically from medical history and co-medications extracted by NLP. The final classification (definite, probable, possible, doubtful) is computed and logged in the audit trail. Compatible with EMA and FDA requirements for causality assessment.
How does the demo work? Can I see PharmaVeil on my own cases? +
Yes, that's exactly our proposition. During the demo (45 min, video call), we process one or more of your real anonymised cases live. You immediately see the result on your own content. No commitment is required at the end of the demo.

Request your personalised
demo.

During the demo (45 min, video call), we process one or more of your real anonymised cases live. You immediately see the value on your own content.

45 minutes, no commitment
Demo on your own cases (anonymised)
Response within 24 business hours
Data hosted in France, GDPR compliant

En soumettant ce formulaire, vous acceptez notre politique de confidentialité. Aucune donnée commerciale. Response within 24 business hours.

Request received!

We will contact you within 24 business hours to schedule your personalised demo.

In the meantime, if you have any urgent questions:
[email protected]